99% Chloroacetic Acid Flakes CH2ClCOOH

Chloroacetic acid, industrially known as monochloroacetic acid (MCA) is the organochlorine compound with the formula ClCH2CO2H. This carboxylic acidis a useful building-block in organic synthesis. Illustrative of its usefulness in organic chemistry is the O-alkylation ofsalicylaldehyde with...

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Chloroacetic acid, industrially known as monochloroacetic acid (MCA) is the organochlorine compound with the formula ClCH2CO2H. This carboxylic acidis a useful building-block in organic synthesis.

Illustrative of its usefulness in organic chemistry is the O-alkylation ofsalicylaldehyde with chloroacetic acid, followed by decarboxylation of the resulting ether, producing benzofuran.

In industry, chloroacetic acid is used in the production of a wide variety of useful compounds; e.g., drugs, dyes, pesticides. Most reactions take advantage of the high reactivity of the C–Cl bond. It is the precursor to the herbicide glyphosate, and the MCPA (2-methyl-4-chlorophenoxyacetic acid) and dimethoate are prepared by alkylation with chloroacetic acid. Chloroacetic acid is converted to chloroacetyl chloride, a precursor to adrenaline (epinephrine). Displacement of chloride by sulfide gives thioglycolic acid, which is used as a stabilizer in PVC and a component in some cosmetics.

In its largest-scale application, chloroacetic acid is used to prepare the thickening agent carboxymethyl cellulose and carboxymethyl starch.

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