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Application Of Pivalic Acid In Medicine

Shandong Minji Chemical Co.,Ltd | Updated: May 15, 2017


Pivalic acid, Trimethylacefic acid, is an important chemical raw materials for pesticides, pharmaceuticals, dyes intermediates, such as pivalic acid, trimethylacetic acid, 2,2-dimethyl propionic acid, , But also for high-grade coatings, Pivalic Acid polymerization initiators, photographic materials, spices, etc., is the most widely used alkyl carboxylic acid one.

Application of pivalic acid in pesticide

The synthesis of a variety of new pesticide fungicides, plant growth regulators and insecticides, such as triadimenol, benzyl chlorotriazole alcohol, triazolone, ), Paclobutrazol, dibenzoylenol, idiopheneazole, ketazolone, tebuconazole, oligosilazole, squad, azazolone and the like. These products have the characteristics of high efficiency, low toxicity, internal absorption, broad spectrum, low dosage and long residual effect. They have good control effect on the pests and diseases such as rice, wheat, soybean, fruit trees and vegetables.

Application of pivalic acid in medicine

Pivaloyl chloride is the production of furosemide, double effect of the adrenal gland table of raw materials, can also be Pivalic Acid used to produce ampicillin, amoxycillin, cefazolin and other semi-synthetic antibiotics. Delethoate prepared by the solution of prednisone good solubility, high efficacy, side effects, can be used for the treatment of rheumatoid arthritis. Benzylpentate can increase the stability of capillaries and can be used to treat tuberculosis. Fentanic acid prepared by pivalic acid can be used as an active ingredient in the treatment of psoriasis ointment.

Application of pivalic acid in initiator

Tert-butyl peroxide produced by the reaction of the acid chloride and tert-butyl peroxide to produce free radicals, the use of temperature can be as low as -50 ℃, with high efficiency, short induction period, short cycle and so on. In addition, it Pivalic Acid is used as a highly efficient initiator, the production of polymer thermal stability, good electrical properties, non-toxic, in the structure of the product with a large molecular weight and good linearity, etc., can be used as food packaging bags.

(HPP), which is a medium-acting initiator, has the characteristics of non-toxic and low-temperature activity, which is a new type of peroxide initiator. The composite initiator system consisting of it and the efficient initiator, bis (2-ethylhexyl) peroxydicarbonate, has many advantages in the production of PVC suspension: it can shorten the polymerization time, the reaction is exothermic and the process is easy to operate. Particle shape is good, "fish eyes" less, narrow molecular weight distribution range, product quality is good.

Especially valeric acid for the synthesis of the initiator there is a great potential, should increase the intensity of research.

Application of pivalic acid in coating

The polyacrylic acid ester coating produced from the initiator made from pivalic acid is obtained by selecting a special structure of the initiator and the chain transfer agent as compared with the conventional initiator, and the synthetic high Pivalic Acid solid content polyacrylate hinge Paint in the aging test showed a higher gloss and light retention performance.

Pivalic acid can also be used to prepare epoxy resin powder coating agent. The powder coating treated with this treatment agent has excellent color and gloss and is difficult to hydrolyze and durable.

Pivalic acid in other applications

Extra valerate has a resistance to hydrolysis and a certain aromatic odor, can be used as a fragrance of shampoo soap. Such as n-propyl pivalate has a fruit flavor, n-amyl valerate has a orchid flavor, methyl pivalate with citrus flavor. Allyl valerate can be used to make hair gel. Polyethylene glycol monoester of pivalic acid can be used as a brake oil for trucks, and its lithium salt is used as an engine fuel additive to increase the octane number. With special valeric acid as a photosensitive material of the coupler, with a small amount of silver consumption, which will help thinning the layer, improve film clarity, coupling reaction speed and so on. In addition, the special valerate can also be used as a metal extractant, wood preservatives, etc., is widely used.


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