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Pivaloyl Chloride Is A Pharmaceutical Intermediate

Shandong Minji Chemical Co.,Ltd | Updated: Jul 05, 2017

Pivaloyl chloride is a very important acylation reagent, mainly used as pharmaceutical intermediates, in many amides and phenolic drugs in the preparation of the main raw materials; has been used for hydroxylamine penicillin and cefadroxil, cephalosporins Oxazoline, bivalirvine adrenaline and other drugs. Pivaloyl Chloride It is also used extensively for the production of pesticide intermediates such as chlorpentanoyl chloride.

Trimethyl acetyl chloride, also known as pivaloyl chloride, is the production of carbamate insecticides azadirachtin intermediates, but also herbicide Isoxazolone intermediates, can be used as synthetic amides and phenolic esters Raw materials for the production of (hydroxyl) ampicillin, Pivaloyl Chloride cephalosporins (hydroxy) ampicillin, cefazolin, bivalirvine adrenal and other drugs, in addition, also used in the synthesis of tert-butyl t-valyl peroxide and so on.

Used as acylating agent for the production of ampicillin and cephalexin and other drug use <for pharmaceutical and pesticide intermediates for the production of ampicillin, cefazolin antibiotics.

Pivaloyl Chloride Use semi-synthetic intermediates of penicillin and cephalosporins, but also pesticide intermediates, photographic materials, organic yellow agent intermediates. Ammonia, Schiff base, pyrrolidone, alcohol acylating agent.

Is an important acylating agent. The main role is as a pharmaceutical intermediates, such as for the production of amoxycillin cephalosporin, cefazolin and bivalencehol adrenaline and other drugs.

Chemical synthesis for the protection of amino groups, Pivaloyl Chloride while increasing the steric effect, easy to get a specific location products.

Colorless and transparent with irritating odor, soluble in a variety of solvents,


Pesticides and pharmaceutical intermediates for the production of ampicillin, cefazolin antibiotics, herbicides ketone (Nongsi it) insecticides, oxazole and pesticide Guangmu Ling, also used in the production of initiator TBPP, photosensitive materials And so on, Pivaloyl Chloride in the polymer polymerization has been widely used.


3,000 tons / year

Specificity of pivaloyl chloride

Danger code: F, T +

Hazard class: 11-14-22-26-34

Safety level: 16-26-36 / 37 / 39-45

UN number: UN2438

Domestic Hazardous Chemical Number: 81117


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